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clinicaltrialsgov-mcp-server

Active·★ 76·Apache-2.0·Updated 2026-05-29
★ Trending★ LLM Infra★ API Integration

MCP server for the ClinicalTrials.gov v2 API. Allow LLMs to search trials, retrieve study details, compare studies, analyze trends, and match patients to eligible trials.

This project provides an MCP server for the ClinicalTrials.gov v2 API, offering five specialized tools to interact with clinical trial data. It enables searching, retrieving details, comparing studies, analyzing trends, and matching patients to eligible trials, running over stdio or HTTP and deployable to Cloudflare Workers.

#TypeScript#Bun#Model Context Protocol#Clinical Trials API#Data Analysis#Cloudflare Workers#Patient Matching
$ Install
$ git clone https://github.com/cyanheads/clinicaltrialsgov-mcp-server.git && cd clinicaltrialsgov-mcp-server && bun install
↗ Visit site★ GitHub
01

Features

01Declarative Tools
02Official ClinicalTrials.gov API Integration
03Advanced Search & Data Analysis
04Patient Matching Capabilities
05Edge-Ready Deployment (Cloudflare Workers)
02

Compatibility

TypeScript
Language
Verified via docs
Bun
Runtime
Verified via docs
Cloudflare Workers
Deployment
Verified via docs
03

Quick start

1
$ git clone https://github.com/cyanheads/clinicaltrialsgov-mcp-server.git
2
$ cd clinicaltrialsgov-mcp-server
3
$ bun install
04

Use cases

↳Find all Phase 3 diabetes studies currently recruiting
↳Get the full details for study NCT03372603
↳What's the status breakdown of all COVID-19 vaccine Phase 3 trials?
↳Compare the study design and eligibility criteria for NCT04516746 and NCT04516759
↳Find recruiting migraine studies in Canada for a 35-year-old female
05

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Related searches

clinicaltrialsgov-mcp-server AlternativesBest API Integration Tools 2026Open Source API Integrationclinicaltrialsgov-mcp-server Tutorialclinicaltrialsgov-mcp-server Vs CompetitorsTypeScriptBunModel Context Protocol

Comments

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  • S
    Sam LewisApr 8, 2026

    Used for systematic review automation in clinical research, accurate trial matching

  • S
    Skyler JohnsonApr 2, 2026

    ClinicalTrials.gov v2 API access for LLMs is exactly what medical research workflows need

  • A
    Alex BrownMar 18, 2026

    The v2 API support means access to the most current trial data and fields

  • Kai Chen
    Kai ChenMar 1, 2026

    Trial search and retrieval coverage is comprehensive, handles complex queries well

On this page
01Features02Compatibility03Quick start04Use cases05Alternatives
Stats
GitHub Stars★ 76
Last commit1d ago
StatusActive
LicenseApache-2.0
CategoryAPI Integration
Trend (30d)
+3↑ 0.7%
Links
Documentation↗Discussion↗Issues↗Releases↗

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